Leo Duan's Research Website

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Hello, thanks for checking out my website.

I’m Leo Duan. I’m a statistician at University of Florida since 2018.

My research aims to build new statistical methods, theory and computational toolboxes for addressing motivating application problems in neuroscience, engineering, and transportation science. The main statistical interest is in modeling the combinatorial objects that are routinely used in science and engineering (e.g., tree graphs, clustering, signal pathways, integer flow networks, etc.). Our research generates interesting solutions at the intersection between combinatorics, optimization, and Bayesian statistics.

My CV can be found here (updated 2025 May)

Some annoucements!

Harnessing Optimization in Bayesian Inference

Sunday, Aug 3: 8:30 AM - 12:30 PM

Bayesian methods offer intuitive frameworks for specifying generative models, quantifying uncertainty, and developing model-based extensions in applications such as multi-population studies. However, traditional Bayesian approaches often face challenges when dealing with high-dimensional data, combinatorial structures, or strict parameter constraints, which can lead to increased costs in modeling, implementation, computation and inference.

This short course introduces and discusses innovative Bayesian methodologies that directly leverage strengths from the optimization literature, significantly broadening the generality and applicability of Bayesian paradigms. These approaches enable researchers to incorporate optimization-based functions or algorithms into various aspects of Bayesian analysis. Examples include accelerated posterior computation via projection-based MCMC, optimization-based reparameterizations that circumvent combinatorial costs, optimization-induced likelihood functions for structured or constrained data, and hybrid models that combine Bayesian and optimization approaches. We will explore different aspects of this framework, including model building, algorithm development, calibration, justification, and statistical inference. The application of these methods will be illustrated through modeling of networks, multivariate time series, and longitudinal or functional data in biomedical and geospatial settings.

Research Interests

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Selected forthcoming work (please email me for latest manuscript):

Selected recent work (pre-print and accepted):

Selected Fundings and Awards

2024 UF CLAS Fellowship for Doctoral Student Supervised

2023-2026 NSF-ATD: Geospatial Modeling and Risk Mitigation for Human Movement Dynamics under Hurricane Threats (PI)

2022 UF CLAS Faculty Travel Award

2022-2023 UFII SEED Funding Award

2021 UF Statistics Faculty Award for Doctoral Student Supervised

2018 NeurIPS Bayesian Non-parametrics Award

2015 ASA Paper Competition Award in Section on Bayesian Statistical Science

2014 Woodside Foundation Award for Contribution in Biostatistics and Epidemiology Research

Recent and Upcoming Talks:

August 2025, EcoSta, Tokyo Japan

August 2025, Joint Statistical Meetings, Nashville TN

June 2025, BayesComp, Singapore

May 2025, Statistical Methods in Imaging Conference, Houston, TX

Current PhD Students

Zeyu Yuwen (Expected to graduate in Spring 2025)

Yu Zheng (Expected to graduate in Fall 2025)

Past Trainees

Cheng Zeng

Edric Tam (Postdoctoral Fellow, Stanford University)

Eleni Dilma (Biostatistician, Food and Drug Administration)

Maoran Xu (Assistant Professor, Indiana University)